Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.44 |
| ▸ | NQO2 | P16083 | 7/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743379 | 0.92 | HTR6 (0.59) | HTR6 | |
| SCHEMBL7743420 | 0.92 | HTR6 (0.59) | HTR6 | |
| SCHEMBL9630431 | 0.85 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2HTR2A | |
| SCHEMBL3288369 | 0.85 | HTR6 (0.60) | HTR6ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL10395043 | 0.84 | MTNR1A (0.59) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7740227 | 0.78 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL3714924 | 0.77 | HTR6 (0.57) | HTR6MTNR1AMTNR1BNQO2 | |
| SCHEMBL2207814 | 0.77 | HTR6 (0.71) | HTR6 | |
| Hydrochloric Acid SCHEMBL9522094 | 0.75 | HTR6 (0.70) | HTR6 | |
| Hydrochloric Acid SCHEMBL30299240 | 0.75 | HTR6 (0.70) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |