Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743420 | 1.00 | HTR6 (0.59) | HTR6SIGMAR1 | |
| SCHEMBL7743375 | 0.92 | HTR6 (0.49) | HTR6 | |
| SCHEMBL2207814 | 0.86 | HTR6 (0.71) | HTR6SIGMAR1 | |
| SCHEMBL3714924 | 0.86 | HTR6 (0.57) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9522094 | 0.85 | HTR6 (0.70) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL30299240 | 0.85 | HTR6 (0.70) | HTR6SIGMAR1 | |
| SCHEMBL3288369 | 0.77 | HTR6 (0.60) | HTR6 | |
| SCHEMBL9630431 | 0.77 | MTNR1A (0.60) | — | |
| SCHEMBL7952263 | 0.76 | MTNR1A (0.61) | SIGMAR1 | |
| SCHEMBL10175562 | 0.76 | SIGMAR1 (0.61) | HTR6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |
| EP-1047664-A1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036392-A1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1999-07-22 | — | — | WO | disclosed |