Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750990 | 0.81 | MAPT (0.55) | MEN1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL3631341 | 0.81 | MAPT (0.55) | MEN1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7743399 | 0.79 | PDK1 (0.42) | HTTMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL4354147 | 0.78 | SMN1; SMN2 (0.55) | HTTMEN1MAPTKMT2ANPSR1 | |
| Carbamic Acid SCHEMBL11483031 | 0.74 | SMN1; SMN2 (0.51) | HTTMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL7743405 | 0.72 | SMN1; SMN2 (0.41) | HTTMEN1MAPTKMT2ALMNA | |
| SCHEMBL10805813 | 0.71 | NAPRT (0.56) | HTTMAPTKMT2ANPSR1LMNA | |
| SCHEMBL3802273 | 0.71 | NAPRT (0.56) | HTTMAPTKMT2ANPSR1LMNA | |
| SCHEMBL10805792 | 0.71 | NAPRT (0.56) | HTTMAPTKMT2ANPSR1LMNA | |
| SCHEMBL7743403 | 0.70 | KMT2A (0.44) | HTTMEN1MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423866-B1 | THERMOLYSIS OF AMMONIUM SALT OF HALOGENATED LOWER ALKYL ACETOACETATE USING MELT | SOLVAYTFLOUR UND DERIVATE GMBH (DE) | 2002-07-23 | — | — | US | disclosed |