Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.72 |
| ▸ | PGR | P06401 | 3/20 | 0.72 |
| ▸ | CNR1 | P21554 | 2/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26228053 | 0.91 | LMNA (0.65) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL21153503 | 0.91 | NR3C1 (0.59) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL23760072 | 0.90 | HIF1A (0.60) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL8502621 | 0.90 | NR3C1 (0.60) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL10337827 | 0.90 | CYP3A4 (0.73) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL7741442 | 0.90 | CYP3A4 (0.73) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL7134775 | 0.90 | CYP3A4 (0.73) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL30885748 | 0.90 | LMNA (0.60) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL20149515 | 0.90 | NR3C1 (0.63) | HIF1ALMNACYP3A4NR3C1PGR | |
| SCHEMBL7741861 | 0.89 | LMNA (0.64) | HIF1ALMNACYP3A4NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502092-B1 | ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | DRACO AB (SE) | 1995-07-26 | — | — | EP | claimed |
| US-6423340-B1 | GASTROINTESTINAL DISORDERS, CROHN'S COLITIS | AKTIEBOLAGET DRACO (SE) | 2002-07-23 | — | — | US | disclosed |
| US-5643602-A | TIME RELEASE PELLETS FOR INTESTINES | ASTRA AKTIEBOLAG (SE) | 1997-07-01 | — | — | US | disclosed |
| EP-0502092-B1 | ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | DRACO AB (SE) | 1995-07-26 | — | — | EP | disclosed |