SCHEMBL7741442

SCHEMBL7741442

CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 6/20 0.73
▸ HIF1A Q16665 6/20 0.73
▸ LMNA P02545 5/20 0.73
▸ NR3C1 P04150 3/20 0.73
▸ PGR P06401 3/20 0.73
▸ NR1I2 O75469 1/20 0.73
▸ NPSR1 Q6W5P4 2/20 0.67
▸ NFKB1 P19838 2/20 0.65
▸ HSD17B10 Q99714 2/20 0.65
▸ BLM P54132 2/20 0.65
▸ PMP22 Q01453 2/20 0.65
▸ CYP2C9 P11712 2/20 0.65
▸ ABCC3 O15438 1/20 0.65
▸ ABCC4 O15439 1/20 0.65
▸ ABCB11 O95342 1/20 0.65
▸ IL5 P05113 1/20 0.65
▸ NR3C2 P08235 1/20 0.65
▸ AR P10275 1/20 0.65
▸ CHRM1 P11229 1/20 0.65
▸ MMP9 P14780 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7134775 1.00 CYP3A4 (0.73) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL10337827 1.00 CYP3A4 (0.73) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL26228053 0.94 LMNA (0.65) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL13985476 0.94 NR3C1 (0.75) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL20149515 0.93 NR3C1 (0.63) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL7741861 0.93 LMNA (0.64) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL7743664 0.90 HIF1A (0.72) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL21153503 0.90 NR3C1 (0.59) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL10352118 0.89 CYP3A4 (0.65) CYP3A4HIF1ALMNANR3C1PGR
SCHEMBL10799262 0.89 CYP3A4 (0.65) CYP3A4HIF1ALMNANR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502092-B1 ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES DRACO AB (SE) 1995-07-26 — — EP claimed
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 — — EP disclosed
EP-3538539-B1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-27 — — EP disclosed
US-12377159-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-08-05 — — US disclosed
US-20240101594-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2024-03-28 — — US disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 — — US disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 — — US disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 — — US disclosed
US-20210252159-A1 CONJUGATES OF CARTILAGE-HOMING PEPTIDES FRED HUTCHINSON CANCER CENTER 2021-08-19 — — US disclosed
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2021-02-11 — — US disclosed
WO-2020146541-A2 TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2020-07-16 — — WO disclosed
US-10711032-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2020-07-14 — — US disclosed
WO-2018089373-A9 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-07-12 — — WO disclosed
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2018-06-07 — — US disclosed
WO-2018089373-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-05-17 — — WO disclosed
US-6423340-B1 GASTROINTESTINAL DISORDERS, CROHN'S COLITIS AKTIEBOLAGET DRACO (SE) 2002-07-23 — — US disclosed
US-5888995-A ANTIINFLAMMATORY AND ANTIALLERGENIC AGENTS; A NOVEL GLUCOCORTICOSTEROID ASTRA AKTIEBOLAG (SE) 1999-03-30 — — US disclosed
US-5643602-A TIME RELEASE PELLETS FOR INTESTINES ASTRA AKTIEBOLAG (SE) 1997-07-01 — — US disclosed
US-5614514-A Steroid esters AKTIEBOLAGET ASTRA (SE) 1997-03-25 — — US disclosed
EP-0502092-B1 ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES DRACO AB (SE) 1995-07-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101594-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 CYP3A4 4139/4885HIF1A 2934/4885LMNA 3616/4885
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 CYP3A4 4146/4885HIF1A 3008/4885LMNA 3817/4885
US-20210252159-A1 CONJUGATES OF CARTILAGE-HOMING PEPTIDES CD44, MATR3, CCL2 CYP3A4 4881/4885HIF1A 1623/4885LMNA 2456/4885
US-10711032-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 CYP3A4 4146/4885HIF1A 3008/4885LMNA 3817/4885
US-20210040144-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 CYP3A4 4139/4885HIF1A 2934/4885LMNA 3616/4885
US-12377159-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 CYP3A4 4139/4885HIF1A 2934/4885LMNA 3616/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 CYP3A4 4139/4885HIF1A 2934/4885LMNA 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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