Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036058 | 0.90 | MAP2K1 (0.50) | ALDH1A1KDM4EIDO1MAP2K2MAP2K1 | |
| SCHEMBL6035378 | 0.87 | MAP2K1 (0.48) | ALDH1A1KDM4EIDO1MAP2K2MAP2K1 | |
| SCHEMBL6035643 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2IDO1MAP2K2 | |
| SCHEMBL6035308 | 0.85 | LMNA (0.47) | ALDH1A1KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL7743790 | 0.83 | TBXA2R (0.48) | ALDH1A1SMN1; SMN2HPGDMGLL | |
| SCHEMBL6035840 | 0.83 | LMNA (0.48) | ALDH1A1LMNATSHR | |
| SCHEMBL6035297 | 0.83 | CYP1A2 (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2IDO1 | |
| SCHEMBL6036070 | 0.82 | LMNA (0.47) | ALDH1A1KDM4ELMNAMAP2K2MAP2K1 | |
| SCHEMBL6035687 | 0.82 | CYP1A2 (0.43) | ALDH1A1KDM4ESMN1; SMN2IDO1MAP2K2 | |
| SCHEMBL6036408 | 0.81 | CYP1A2 (0.49) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002532414-A | — | — | 2002-10-02 | — | — | JP | claimed |
| EP-1140046-A1 | USE OF A MEK INHIBITOR FOR PREVENTING TRANSPLANT REJECTION | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035435-A1 | USE OF A MEK INHIBITOR FOR PREVENTING TRANSPLANT REJECTION | WARNER-LAMBERT COMPANY (US) | 2000-06-22 | — | — | WO | claimed |