Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 7/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408738 | 1.00 | ADORA2A (0.52) | ADORA2AADORA3HSP90B1PI4KAPI4K2B | |
| SCHEMBL6222357 | 0.85 | ADORA2A (0.50) | ADORA2AADORA3HSP90B1PI4KAPI4K2B | |
| SCHEMBL2821282 | 0.85 | ADORA2A (0.58) | ADORA2AADORA3HSP90B1PI4KAPI4K2B | |
| SCHEMBL19692161 | 0.84 | ADORA2A (0.58) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL1078828 | 0.84 | ADORA2A (0.64) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL11040343 | 0.84 | ADORA2A (0.58) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL28156591 | 0.84 | ADORA2A (0.64) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL8943715 | 0.83 | ADORA2A (0.57) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5554234 | 0.83 | ADORA2A (0.56) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL9054202 | 0.82 | ADORA2A (0.55) | ADORA2AADORA3HSP90B1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708781-B1 | A 3 ADENOSINE RECEPTOR AGONISTS | USA (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0708781-A1 | A 3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002604-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-01-26 | — | — | WO | disclosed |