Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 19/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 18/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 18/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221665 | 1.00 | ADORA3 (0.61) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7455077 | 0.95 | PGK1 (0.57) | ADORA3ADORA2AADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL7223291 | 0.95 | PGK1 (0.57) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7456399 | 0.92 | PGK1 (0.53) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7230980 | 0.92 | ADORA3 (0.69) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5086139 | 0.91 | PGK1 (0.51) | ADORA3ADORA2AADORA2BADORA1 | |
| Formic Acid SCHEMBL7224962 | 0.89 | PGK1 (0.50) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7463425 | 0.89 | ADORA2A (0.67) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7455750 | 0.88 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1 | |
| Formic Acid SCHEMBL7223839 | 0.88 | PGK1 (0.48) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | disclosed |
| EP-0948509-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028319-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-07-02 | — | — | WO | disclosed |