Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.53 |
| ▸ | PGK2 | P07205 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7224962 | 0.97 | PGK1 (0.50) | PGK1PGK2ADORA3ADORA2AADORA2B | |
| SCHEMBL7454558 | 0.95 | PGK1 (0.60) | PGK1PGK2ADORA3ADORA2AADORA2B | |
| SCHEMBL7744378 | 0.92 | ADORA3 (0.61) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7221665 | 0.92 | ADORA3 (0.61) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7465380 | 0.92 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1 | |
| Formic Acid SCHEMBL7230198 | 0.92 | PGK1 (0.56) | PGK1PGK2ADORA3ADORA2AADORA2B | |
| SCHEMBL5086139 | 0.92 | PGK1 (0.51) | PGK1PGK2ADORA3ADORA2AADORA2B | |
| SCHEMBL7452812 | 0.90 | ADORA2A (0.59) | PGK1PGK2ADORA3ADORA2AADORA2B | |
| SCHEMBL7224964 | 0.90 | PGK1 (0.45) | PGK1PGK2ADORA3ADORA2AADORA2B | |
| SCHEMBL7224970 | 0.90 | PGK1 (0.46) | PGK1PGK2ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | claimed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | claimed |