Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7744387

Cc1c(O)cccc1S(=O)(=O)O.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
ATM Q13315 1/20 0.46
AURKA O14965 1/20 0.43
AURKB Q96GD4 1/20 0.43
MYC P01106 1/20 0.43
CDK2 P24941 1/20 0.42
TTR P02766 1/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ESR2 Q92731 2/20 0.38
GAA P10253 2/20 0.38
ESR1 P03372 1/20 0.38
STAT3 P40763 1/20 0.38
EDNRA P25101 1/20 0.37
NR4A1 P22736 1/20 0.37
RPS6KA3 P51812 1/20 0.37
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34452 0.98 TRPA1 (0.48) TRPA1ATMAURKAAURKBMYC
SCHEMBL29881857 0.98 TRPA1 (0.48) TRPA1ATMAURKAAURKBMYC
SCHEMBL28228158 0.96 TRPA1 (0.46) TRPA1ATMAURKAAURKBMYC
SCHEMBL17272019 0.96 TRPA1 (0.46) TRPA1ATMAURKAAURKBMYC
SCHEMBL27632967 0.96 TRPA1 (0.46) TRPA1ATMAURKAAURKBMYC
SCHEMBL9473186 0.96 TRPA1 (0.46) TRPA1ATMAURKAAURKBMYC
SCHEMBL17272185 0.96 TRPA1 (0.46) TRPA1ATMAURKAAURKBMYC
Formaldehyde SCHEMBL958923 0.94 TRPA1 (0.45) TRPA1ATMAURKAAURKBMYC
Benzene SCHEMBL28203203 0.94 TRPA1 (0.45) TRPA1ATMAURKAAURKBMYC
SCHEMBL27719923 0.90 TRPA1 (0.42) TRPA1ATMAURKAAURKBMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9718905-B2 Polythiophene, water-soluble electrically conductive polymer using it, and method for producing it TOSOH CORPORATION (JP) 2017-08-01 US disclosed
CN-104428341-B Polythiophene class, the water-soluble conducting polymer using it and manufacture method thereof 东曹株式会社 2016-10-26 CN disclosed
US-20150337061-A1 POLYTHIOPHENE, WATER-SOLUBLE ELECTRICALLY CONDUCTIVE POLYMER USING IT, AND METHOD FOR PRODUCING IT TOSOH CORPORATION (JP) 2015-11-26 US disclosed
CN-104428341-A Polythiophenes, water-soluble conductive polymer using same, and method for producing same TOSOH CORP 2015-03-18 CN disclosed
CN-1469709-A Allergen neutralization compositions 2004-01-21 CN disclosed
CN-1454053-A Allergen neutralization compositions PROCTER & GAMBLE (US) 2003-11-05 CN disclosed
US-20020150540-A1 Allergen neutralization compositions containing aluminum ions THE PROCTER & GAMBLE COMPANY 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020150540-A1 Allergen neutralization compositions containing aluminum ions CAT, CA2, LCT TRPA1 816/4885ATM 2266/4885AURKA 3254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.