Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524005 | 0.72 | NPSR1 (0.54) | NPSR1EPHX2KDM4ELMNAGFER | |
| SCHEMBL16630325 | 0.71 | KMT2A (0.54) | NPSR1EPHX2LMNAALDH1A1KMT2A | |
| SCHEMBL14152198 | 0.70 | GAA (0.35) | NPSR1EPHX2GAAKDM4ELMNA | |
| SCHEMBL16629746 | 0.69 | LMNA (0.49) | NPSR1EPHX2LMNAALDH1A1KMT2A | |
| SCHEMBL14152565 | 0.67 | CNR2 (0.43) | GAAKMT2A | |
| SCHEMBL38661956 | 0.66 | RAB9A (0.45) | NPSR1EPHX2GAAKDM4ELMNA | |
| SCHEMBL17645696 | 0.66 | MEN1 (0.33) | GAAKMT2A | |
| SCHEMBL29168097 | 0.66 | RAB9A (0.38) | NPSR1EPHX2GAAKDM4ELMNA | |
| SCHEMBL4788987 | 0.65 | APLNR (0.36) | NPSR1GAAKDM4ELMNAGFER | |
| SCHEMBL14152731 | 0.63 | CNR2 (0.43) | GAAKDM4ELMNAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918534-A4 | PEPTIDYL PRODRUGS AND METHODS OF MAKING AND USING THE SAME | UNIV PITTSBURGH (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-0918534-A1 | PEPTIDYL PRODRUGS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004277-A1 | PEPTIDYL PRODRUGS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1998-02-05 | — | — | WO | disclosed |