Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL30070584 | 0.88 | — | — | |
| Glycine SCHEMBL6675874 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL13169653 | 0.88 | — | — | |
| Glycine SCHEMBL391027 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL6163 | 0.88 | — | — | |
| Glycine SCHEMBL2116443 | 0.88 | — | — | |
| Glycine SCHEMBL93765 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL3640989 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391786 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL29385054 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867986-B | Polymer modified nano calcium carbonate product series | 厦门大学 | 2020-10-27 | — | — | CN | disclosed |
| WO-2020018839-A1 | COMPOUNDS AND METHODS FOR SYNERGISTIC ACTIVATION OF M CHANNELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-01-23 | — | — | WO | disclosed |
| CN-109867986-A | A kind of macromolecule modified nanometer calcium carbonate new product family | 厦门大学 | 2019-06-11 | — | — | CN | disclosed |
| US-6329497-B1 | ANTITUMOR AGENTS; VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS | THE SCRIPPS RESEARCH INSTITUTE | 2001-12-11 | — | — | US | disclosed |
| EP-0996458-A4 | SANDRAMYCIN ANALOGS | SCRIPPS RESEARCH INST (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0996458-A1 | SANDRAMYCIN ANALOGS | The Scripps Research Institute (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1998043663-A1 | SANDRAMYCIN ANALOGS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-10-08 | — | — | WO | disclosed |