Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 3/20 | 0.37 |
| ▸ | POLQ | O75417 | 4/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744128 | 0.87 | KCNH2 (0.52) | KCNH2XIAPPOLQP2RX7SCN9A | |
| SCHEMBL7744000 | 0.84 | KCNH2 (0.55) | KCNH2XIAPPOLQP2RX7 | |
| SCHEMBL7744124 | 0.84 | KCNH2 (0.55) | KCNH2XIAPPOLQP2RX7 | |
| SCHEMBL7744593 | 0.79 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL7744135 | 0.79 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL7036498 | 0.72 | KCNH2 (0.47) | KCNH2XIAPPOLQP2RX7SCN9A | |
| SCHEMBL8760273 | 0.71 | KCNH2 (0.75) | KCNH2 | |
| SCHEMBL7854689 | 0.70 | KCNH2 (0.47) | KCNH2POLQP2RX7SCN9A | |
| SCHEMBL7036494 | 0.70 | KCNH2 (0.57) | KCNH2XIAPPOLQSCN9A | |
| SCHEMBL7743998 | 0.70 | KCNH2 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010216-A1 | ANTIARRHYTHMIC COMPOUNDS | MERCK & CO., INC. (US) | 2001-02-15 | — | — | WO | disclosed |