Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 3/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744802 | 0.84 | CCR5 (0.47) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7745335 | 0.84 | KMT2A (0.45) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7745400 | 0.82 | KDM4E (0.43) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7744834 | 0.82 | GAA (0.46) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7744782 | 0.82 | GAA (0.53) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7744827 | 0.82 | KDM4E (0.49) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7744853 | 0.81 | MAPT (0.46) | CCR5IDECLK1NTSR1ALDH1A1 | |
| SCHEMBL7744874 | 0.81 | MALT1 (0.44) | CCR5IDECLK1KDM4EMAPT | |
| SCHEMBL7745248 | 0.80 | CCR5 (0.45) | CCR5IDECLK1ALDH1A1KMT2A | |
| SCHEMBL7745260 | 0.80 | NTSR1 (0.42) | CCR5IDECLK1NTSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | claimed |
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |