Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 3/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747563 | 0.90 | IDE (0.45) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7740114 | 0.87 | IDE (0.45) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7745262 | 0.87 | CCR5 (0.43) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7744835 | 0.86 | IDE (0.46) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7745335 | 0.86 | KMT2A (0.45) | CCR5IDECLK1ALDH1A1KMT2A | |
| SCHEMBL7745238 | 0.86 | CCR5 (0.42) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7740294 | 0.85 | CCR5 (0.40) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7745349 | 0.85 | CCR5 (0.40) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7745343 | 0.85 | CCR5 (0.40) | CCR5IDECLK1PTGS1CYP2C19 | |
| SCHEMBL7740033 | 0.85 | IDE (0.52) | CCR5IDECLK1PTGS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | claimed |
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |