Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747635 | 0.90 | L3MBTL1 (0.31) | HSD11B1TRPM8NR1I2 | |
| SCHEMBL7740256 | 0.81 | NR3C2 (0.36) | NR3C2HSD11B1TRPM8 | |
| SCHEMBL7753809 | 0.80 | — | — | |
| SCHEMBL7754491 | 0.80 | — | — | |
| SCHEMBL7744842 | 0.78 | NR3C2 (0.34) | NR3C2HSD11B1 | |
| SCHEMBL7755890 | 0.78 | TP53 (0.36) | — | |
| SCHEMBL7744854 | 0.75 | — | — | |
| SCHEMBL7744872 | 0.72 | — | — | |
| SCHEMBL7744815 | 0.71 | TSHR (0.34) | NR3C2HSD11B1TRPM8 | |
| SCHEMBL7745401 | 0.67 | TP53 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1305466-A | Substituted phenyl pyridazinones | BAYER AG (DE) | 2001-07-25 | — | — | CN | disclosed |
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |