Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338280 | 0.81 | LMNA (0.75) | LMNAPKMDDAH1BCHEPOLB | |
| SCHEMBL13909625 | 0.74 | CXCR4 (0.58) | LMNAPKMALDH1A1 | |
| SCHEMBL4111972 | 0.72 | IDO1 (0.70) | LMNAPKMDDAH1BCHEPOLB | |
| SCHEMBL31298007 | 0.72 | PKM (0.96) | LMNAPKMDDAH1BCHEPOLB | |
| SCHEMBL336412 | 0.72 | PKM (0.96) | LMNAPKMDDAH1BCHEPOLB | |
| SCHEMBL31734838 | 0.71 | PKM (0.71) | PKMDDAH1BCHEPOLBSMN1; SMN2 | |
| SCHEMBL711507 | 0.71 | PKM (0.71) | PKMDDAH1BCHEPOLBSMN1; SMN2 | |
| SCHEMBL13899002 | 0.71 | PKM (0.66) | PKMDDAH1BCHEPOLBSMN1; SMN2 | |
| SCHEMBL6759257 | 0.71 | IDO1 (0.68) | LMNAPKMDDAH1BCHEPOLB | |
| Hydrochloric Acid SCHEMBL5973175 | 0.70 | PKM (1.00) | LMNAPKMDDAH1BCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |