Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759257 | 0.98 | IDO1 (0.68) | IDO1LMNAGRIN2BGRIN1AAK1 | |
| SCHEMBL1825671 | 0.93 | IDO1 (0.79) | IDO1LMNAGRIN2BGRIN1DDAH1 | |
| SCHEMBL3701887 | 0.87 | IDO1 (0.67) | IDO1LMNAGRIN2BGRIN1DDAH1 | |
| SCHEMBL1299032 | 0.87 | IDO1 (0.67) | IDO1LMNAGRIN2BGRIN1DDAH1 | |
| SCHEMBL23111745 | 0.85 | IDO1 (0.65) | IDO1LMNAGRIN2BGRIN1DDAH1 | |
| SCHEMBL7083093 | 0.85 | IDO1 (0.74) | IDO1GRIN2BGRIN1DDAH1POLB | |
| SCHEMBL6757232 | 0.85 | LMNA (0.62) | IDO1LMNADDAH1POLBHTT | |
| SCHEMBL2030001 | 0.85 | IDO1 (0.57) | IDO1LMNAGRIN2BGRIN1AAK1 | |
| SCHEMBL4110878 | 0.84 | LMNA (0.64) | IDO1LMNADDAH1POLBHTT | |
| SCHEMBL21034378 | 0.83 | IDO1 (1.00) | IDO1GRIN2BGRIN1DDAH1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976187-A1 | METHODS AND COMPOSITIONS FOR TREATING EPILEPSY | The Regents of the University of California (US) | 2022-04-06 | — | — | EP | disclosed |
| CN-114007692-A | Methods and compositions for treating epilepsy | 加利福尼亚大学董事会 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020243349-A1 | METHODS AND COMPOSITIONS FOR TREATING EPILEPSY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-03 | — | — | WO | disclosed |
| WO-2020243349-A1 | METHODS AND COMPOSITIONS FOR TREATING EPILEPSY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-03 | — | — | WO | disclosed |
| WO-2007117778-A9 | QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS INC (US) | 2009-05-22 | — | — | WO | disclosed |
| EP-1986747-A2 | QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | Kalypsys, Inc. (US) | 2008-11-05 | — | — | EP | disclosed |
| US-20080139558-A1 | QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2007117778-A2 | QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139558-A1 | QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | NOS2, NOS1, NQO2 | IDO1 160/4885LMNA 2981/4885GRIN2B 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.