Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255168 | 0.81 | GLA (0.44) | MAPTLMNAALDH1A1GLATDP1 | |
| SCHEMBL1317029 | 0.79 | TDP1 (0.43) | MAPTLMNAALDH1A1L3MBTL1GLA | |
| SCHEMBL3294525 | 0.76 | TDP1 (0.51) | MAPTLMNAALDH1A1GLATDP1 | |
| SCHEMBL364235 | 0.74 | AKR1C3 (0.53) | MAPTLMNAALDH1A1GLATDP1 | |
| SCHEMBL4949600 | 0.74 | GLA (0.49) | MAPTLMNAALDH1A1L3MBTL1GLA | |
| SCHEMBL461687 | 0.74 | MAPT (0.37) | MAPTLMNAALDH1A1L3MBTL1GLA | |
| SCHEMBL8386806 | 0.72 | GLA (0.50) | MAPTLMNAALDH1A1L3MBTL1GLA | |
| SCHEMBL5676356 | 0.72 | GLA (0.42) | MAPTLMNAALDH1A1L3MBTL1GLA | |
| SCHEMBL2334120 | 0.72 | MAOB (0.40) | MAPTLMNAALDH1A1L3MBTL1GLA | |
| SCHEMBL8730748 | 0.72 | GLA (0.42) | MAPTLMNAALDH1A1L3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021303-A1 | AN IMPROVED METHOD AND APPARATUS FOR DEVOLATILIZATION | THE DOW CHEMICAL COMPANY (US) | 2001-03-29 | — | — | WO | disclosed |