SCHEMBL1317029

SCHEMBL1317029

CC(=C(C=CC#N)C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
GLA P06280 1/20 0.43
MAPT P10636 9/20 0.42
LMNA P02545 4/20 0.42
MAOB P27338 3/20 0.42
CYP1B1 Q16678 2/20 0.42
PLIN1 O60240 2/20 0.42
RECQL P46063 2/20 0.42
PLIN5 Q00G26 2/20 0.42
ABHD5 Q8WTS1 2/20 0.42
BCHE P06276 1/20 0.42
TNFRSF1A P19438 1/20 0.42
ACHE P22303 1/20 0.42
ALOX15 P16050 1/20 0.41
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 3/20 0.40
HDAC3 O15379 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2334120 0.85 MAOB (0.40) TDP1GLAMAPTLMNAMAOB
Acrylonitrile SCHEMBL9249177 0.81 GLA (0.38) TDP1GLAMAPTLMNAMAOB
SCHEMBL2729308 0.80 HDAC3 (0.33) L3MBTL1KMT2AHDAC3HDAC4HDAC1
SCHEMBL5676356 0.80 GLA (0.42) TDP1GLAMAPTLMNAMAOB
SCHEMBL7744975 0.79 MAPT (0.44) TDP1GLAMAPTLMNAMAOB
SCHEMBL7060139 0.76 TDP1 (0.44) TDP1GLAMAPTLMNAMAOB
SCHEMBL1404410 0.73 GLA (0.52) TDP1GLAMAPTLMNAMAOB
SCHEMBL461687 0.73 MAPT (0.37) TDP1GLAMAPTLMNAMAOB
SCHEMBL1034440 0.72 CYP3A4 (0.46) TDP1GLAMAPTLMNAMAOB
SCHEMBL19591781 0.71 GLA (0.46) TDP1GLAMAPTLMNAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3561368-A1 LIGHTING MODULE COMPRISING COLOR CONVERSION FILM LG Chem, Ltd. (KR) 2019-10-30 EP claimed
US-4692295-A USING A LOWER STRETCHING FORCE BY INCLUDING A HIGH MOLECULAR WEIGHT ADDITIVE ADDITION POLYMER PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1987-09-08 US claimed
EP-3561368-A1 LIGHTING MODULE COMPRISING COLOR CONVERSION FILM LG Chem, Ltd. (KR) 2019-10-30 EP disclosed
US-20110274932-A1 COMPONENT COMPRISING AN INSERT PART AND PLASTICS JACKETING, AND PROCESS FOR PRODUCTION OF THE COMPONENT BASF SE (DE) 2011-11-10 US disclosed
US-5248546-A Insulation THE B. F. GOODRICH COMPANY (US) 1993-09-28 US disclosed
EP-0529576-A1 Vinyl based articles in contact with chloro-fluoro chemicals The Geon Company (US) 1993-03-03 EP disclosed
EP-0185337-B1 PROCESS FOR PREPARING PHOTOPOLYMER FLEXOGRAPHIC ELEMENT WITH MELT EXTRUSION COATED ELASTOMERIC SURFACE LAYER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-06 EP disclosed
US-4772425-A HIGH FOAMING, ANIONIC SURFACTANTS, DIATOMACEOUS EARTH COLGATE-PALMOLIVE COMPANY (US) 1988-09-20 US disclosed
EP-0265275-A2 High impact polyarylate compositions HOECHST CELANESE CORPORATION (US) 1988-04-27 EP disclosed
US-4622088-A PRINTING PLATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-11 US disclosed
EP-0185337-A2 Process for preparing photopolymer flexographic element with melt extrusion coated elastomeric surface layer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-25 EP disclosed