SCHEMBL5676356

SCHEMBL5676356

C=CC(C)=C(C=CC#N)C=Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALOX15 P16050 1/20 0.40
LMNA P02545 4/20 0.37
MAPT P10636 3/20 0.37
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
PLIN1 O60240 2/20 0.37
RECQL P46063 2/20 0.37
PLIN5 Q00G26 2/20 0.37
ABHD5 Q8WTS1 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TNKS O95271 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC10 Q969S8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1317029 0.80 TDP1 (0.43) GLATDP1ALOX15LMNAMAPT
SCHEMBL11031369 0.75 KDM4E (0.35) GLATDP1ALOX15LMNAMAPT
SCHEMBL624043 0.73 GLA (0.41) GLATDP1LMNAMAPTHDAC3
SCHEMBL8386806 0.73 GLA (0.50) GLATDP1ALOX15LMNAMAPT
SCHEMBL9124797 0.72 ALDH1A1 (0.39) GLATDP1LMNAMAPTALDH1A1
SCHEMBL7744975 0.72 MAPT (0.44) GLATDP1LMNAMAPTHDAC3
SCHEMBL116598 0.72 LMNA (0.39) GLATDP1ALOX15LMNAMAPT
SCHEMBL6013130 0.72 CYP3A4 (0.47) GLATDP1ALOX15LMNAMAPT
SCHEMBL1404410 0.72 GLA (0.52) GLATDP1ALOX15LMNAMAPT
SCHEMBL461687 0.71 MAPT (0.37) GLATDP1LMNAMAPTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1258518-B1 Flame-retardant curable resin composition and flame-retardant curable adhesive composition DENKI KAGAKU KOGYO KK (JP) 2006-01-04 EP claimed