Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33889 | 0.91 | ACHE (0.46) | ACHEENPP2CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL7628216 | 0.89 | ACHE (0.44) | ACHECHRM5CHRM1CHRM3ADRA2A | |
| Hydrochloric Acid SCHEMBL525772 | 0.89 | ACHE (0.44) | ACHEBBOX1ENPP2CHRM5CHRM1 | |
| Iodide SCHEMBL8612631 | 0.89 | ACHE (0.44) | ACHECHRM5CHRM1CHRM3ADRA2A | |
| SCHEMBL4091792 | 0.89 | POLB (0.39) | ACHEBBOX1ENPP2CHRM5CHRM1 | |
| SCHEMBL11528594 | 0.85 | ACHE (0.35) | ACHEBBOX1ENPP2CHRM5CHRM1 | |
| SCHEMBL11781192 | 0.82 | LMNA (0.40) | CYP2C19POLBGAARAB9A | |
| SCHEMBL21457873 | 0.78 | ACHE (0.60) | ACHEBBOX1ENPP2CHRM5CHRM1 | |
| SCHEMBL18690276 | 0.78 | ACHE (0.46) | ACHEBBOX1ENPP2CHRM5CHRM1 | |
| SCHEMBL8169689 | 0.78 | POLB (0.37) | ACHEBBOX1ENPP2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331593-B1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | SOLENIS TECHNOLOGIES CAYMAN LP (CH) | 2016-02-24 | — | — | EP | claimed |
| US-9034146-B2 | Copolymer blend compositions for use to increase paper filler content | SOLENIS TECHNOLOGIES, L.P. (CH) | 2015-05-19 | — | — | US | claimed |
| US-8518216-B2 | Copolymer blend compositions for use to increase paper filler content | HERCULES INCORPORATED (US) | 2013-08-27 | — | — | US | claimed |
| US-20120071608-A1 | Copolymer Blend Compositions for Use to Increase Paper Filler Content | HERCULES INCORPORATED | 2012-03-22 | — | — | US | claimed |
| EP-2331593-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | Hercules Incorporated (US) | 2011-06-15 | — | — | EP | claimed |
| WO-2010033796-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | WO | claimed |
| US-20100071863-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | US | claimed |
| EP-2331593-B1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | SOLENIS TECHNOLOGIES CAYMAN LP (CH) | 2016-02-24 | — | — | EP | disclosed |
| US-9034146-B2 | Copolymer blend compositions for use to increase paper filler content | SOLENIS TECHNOLOGIES, L.P. (CH) | 2015-05-19 | — | — | US | disclosed |
| US-20140318728-A1 | Copolymer Blend Compositions For Use To Increase Paper Filler Content | HERCULES INCORPORATED (US) | 2014-10-30 | — | — | US | disclosed |
| US-8518216-B2 | Copolymer blend compositions for use to increase paper filler content | HERCULES INCORPORATED (US) | 2013-08-27 | — | — | US | disclosed |
| US-8163134-B2 | Copolymer blend compositions for use to increase paper filler content | HERCULES INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |
| US-20120071608-A1 | Copolymer Blend Compositions for Use to Increase Paper Filler Content | HERCULES INCORPORATED | 2012-03-22 | — | — | US | disclosed |
| EP-2331593-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | Hercules Incorporated (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010033796-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20100071863-A1 | COPOLYMER BLEND COMPOSITIONS FOR USE TO INCREASE PAPER FILLER CONTENT | HERCULES INC. (US) | 2010-03-25 | — | — | US | disclosed |