Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.44 |
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33889 | 0.98 | ACHE (0.46) | ACHECHRM5CHRM1CHRM3BLM | |
| Iodide SCHEMBL8612631 | 0.95 | ACHE (0.44) | ACHECHRM5CHRM1CHRM3BLM | |
| Bromide SCHEMBL7628216 | 0.95 | ACHE (0.44) | ACHECHRM5CHRM1CHRM3BLM | |
| Sulfuric Acid SCHEMBL774507 | 0.89 | ACHE (0.40) | ACHECHRM5CHRM1CHRM3BLM | |
| Hydrochloric Acid SCHEMBL8166002 | 0.86 | ACHE (0.41) | ACHECHRM5CHRM1CHRM3BLM | |
| Hydrochloric Acid SCHEMBL15419542 | 0.86 | ACHE (0.58) | ACHECHRM5CHRM1CHRM3BLM | |
| SCHEMBL21457873 | 0.84 | ACHE (0.60) | ACHECHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL29000065 | 0.83 | ACHE (0.54) | ACHECHRM5CHRM1CHRM3BLM | |
| SCHEMBL4091792 | 0.82 | POLB (0.39) | ACHECHRM5CHRM1CHRM3BLM | |
| SCHEMBL11528594 | 0.82 | ACHE (0.35) | ACHECHRM5CHRM1CHRM3BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028892-A | Composition for conditioning hair | 莱雅公司 | 2026-05-12 | — | — | CN | claimed |
| US-20250186330-A1 | COSMETIC MATERIAL COMPOSITION AND FIBER TREATMENT COMPOSITION FOR HEAD DECORATION PRODUCTS | KAO CORPORATION (JP) | 2025-06-12 | — | — | US | claimed |
| EP-4534071-A1 | COSMETIC MATERIAL COMPOSITION AND FIBER TREATMENT COMPOSITION FOR HEAD DECORATION PRODUCTS | Kao Corporation (JP) | 2025-04-09 | — | — | EP | claimed |
| EP-4534152-A1 | AQUEOUS COMPOSITION FOR BODY | Kao Corporation (JP) | 2025-04-09 | — | — | EP | claimed |
| CN-119278023-A | Fiber treatment composition for cosmetic or hair wear | 花王株式会社 | 2025-01-07 | — | — | CN | claimed |
| US-11938207-B2 | Cosmetic composition for skin | KAO CORPORATION (JP) | 2024-03-26 | — | — | US | claimed |
| CN-113499782-B | Preparation method of hollow mesoporous silica dissolution regeneration limited-domain cobalt molybdate catalyst and catalytic oxidation diesel desulfurization method | 江苏大学 | 2024-03-01 | — | — | CN | claimed |
| WO-2023234192-A1 | COSMETIC MATERIAL COMPOSITION AND FIBER TREATMENT COMPOSITION FOR HEAD DECORATION PRODUCTS | 花王株式会社 | 2023-12-07 | — | — | WO | claimed |
| WO-2023234190-A1 | AQUEOUS COMPOSITION FOR BODY | 花王株式会社 | 2023-12-07 | — | — | WO | claimed |
| CN-116874680-A | Emulsion type silicone oil modified polyacrylamide and preparation method and application thereof | 杭州传化精细化工有限公司 | 2023-10-13 | — | — | CN | claimed |
| EP-0213317-A2 | Base-catalyzed, low temperature self-crosslinking polymers | National Starch and Chemical Investment Holding Corporation (US) | 1987-03-11 | — | — | EP | claimed |
| EP-0082571-B1 | A METHOD FOR CLARIFYING COAL LIQUORS WITH WATER-SOLUBLE, HIGH MOLECULAR WEIGHT POLYMERS HAVING LOW CONCENTRATION OF CATIONIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1986-10-29 | — | — | EP | claimed |
| EP-0107226-B1 | WATER-IN-OIL EMULSIONS OF WATER-SOLUBLE CATIONIC POLYMERS AND A PROCESS FOR PREPARING SUCH EMULSIONS | THE DOW CHEMICAL COMPANY (US) | 1986-09-10 | — | — | EP | claimed |
| EP-0188721-A1 | Inverse emulsion polymers with improved incorporation of diallyldimethylammonium chloride | ALLIED CORPORATION (US) | 1986-07-30 | — | — | EP | claimed |
| US-4486554-A | Preparation of anionic and cationic polymers from 2-oxazolines | THE DOW CHEMICAL COMPANY (US) | 1984-12-04 | — | — | US | claimed |
| US-4464508-A | ADDING SALT TO AQUEOUS PHASE PRIOR TO POLYMERIZING | THE DOW CHEMICAL COMPANY (US) | 1984-08-07 | — | — | US | claimed |
| EP-0107226-A2 | Water-in-oil emulsions of water-soluble cationic polymers and a process for preparing such emulsions | THE DOW CHEMICAL COMPANY (US) | 1984-05-02 | — | — | EP | claimed |
| EP-0082571-A1 | A method for clarifying coal liquors with water-soluble, high molecular weight polymers having low concentration of cationic moieties | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | claimed |
| US-4386336-A | Humidity sensor and a humidity detection circuit using the humidity sensor | SHINYEI KAISHA (JP) | 1983-05-31 | — | — | US | claimed |
| US-4376850-A | BOROHYDRIDE INITIATORS | THE DOW CHEMICAL COMPANY (US) | 1983-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11938207-B2 | Cosmetic composition for skin | CUTA, SSB, BCAS2 | ACHE 1134/4885CHRM1 3006/4885CHRM3 3500/4885 |
| US-20250186330-A1 | COSMETIC MATERIAL COMPOSITION AND FIBER TREATMENT COMPOSITION FOR HEAD DECORATION PRODUCTS | H1-0, DEGS1, CUTA | ACHE 1403/4885CHRM1 375/4885CHRM3 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.