SCHEMBL7745183

SCHEMBL7745183

O=CNc1ccc(NC=O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.59
SYK P43405 1/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ESR2 Q92731 1/20 0.35
PABPC1 P11940 1/20 0.34
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL28124303 0.88 KDM5A (0.49) KDM5ASYKALDH1A1LMNAKDM4E
SCHEMBL5457643 0.83 EGFR (0.47) KDM5AALDH1A1KDM4ERAB9AEGFR
SCHEMBL8574587 0.82 KDM5A (0.46) KDM5ASYKALDH1A1GAARAB9A
SCHEMBL3562018 0.81 KDM5A (0.61) KDM5ASYKALDH1A1LMNAKDM4E
Pyridine SCHEMBL28839856 0.80 KDM5A (0.44) KDM5ASYKALDH1A1
SCHEMBL7745818 0.78 ALOX15 (0.45) KDM5AALDH1A1LMNAKDM4EGAA
SCHEMBL6838321 0.78 KDM5A (0.58) KDM5AALDH1A1LMNAKDM4EGAA
SCHEMBL28009999 0.78 ALDH1A1 (0.49) ALDH1A1LMNAGAARAB9ANPC1
SCHEMBL12635347 0.78 ALDH1A1 (0.40) KDM5AALDH1A1LMNAKDM4EGAA
SCHEMBL13367921 0.78 KDM5A (0.58) KDM5ASYKALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106496253-A A kind of multi-functional zinc/cadmium complex of thiophene phenyl organic ligand and its application 渤海大学 2017-03-15 CN claimed
EP-1113006-A1 Process for the synthesis of 2,5-dicarbonamidophenolic couplers and benzoxazole derivatives as intermediates EASTMAN KODAK COMPANY (US) 2001-07-04 EP claimed
US-6201125-B1 REDUCING A 2-ALKYL-6-NITRO-BENZOXAZOLE TO FORM A 2-ALKYL-6-AMINO-BENZOXAZOLE IN WHICH THE 2-ALKYL GROUP IS UNBRANCHED AT THE ALPHA CARBON; COUPLERS EASTMAN KODAK COMPANY 2001-03-13 US claimed
US-5853968-A Multilayer color photographic element EASTMAN KODAK COMPANY (US) 1998-12-29 US claimed
CN-106496253-B A kind of multi-functional zinc/cadmium complex of thiophene phenyl organic ligand and its application 渤海大学 2018-06-08 CN disclosed
CN-106496253-A A kind of multi-functional zinc/cadmium complex of thiophene phenyl organic ligand and its application 渤海大学 2017-03-15 CN disclosed
EP-1113006-A1 Process for the synthesis of 2,5-dicarbonamidophenolic couplers and benzoxazole derivatives as intermediates EASTMAN KODAK COMPANY (US) 2001-07-04 EP disclosed
EP-1113006-A1 Process for the synthesis of 2,5-dicarbonamidophenolic couplers and benzoxazole derivatives as intermediates EASTMAN KODAK COMPANY (US) 2001-07-04 EP disclosed
US-6201125-B1 REDUCING A 2-ALKYL-6-NITRO-BENZOXAZOLE TO FORM A 2-ALKYL-6-AMINO-BENZOXAZOLE IN WHICH THE 2-ALKYL GROUP IS UNBRANCHED AT THE ALPHA CARBON; COUPLERS EASTMAN KODAK COMPANY 2001-03-13 US disclosed
US-6201125-B1 REDUCING A 2-ALKYL-6-NITRO-BENZOXAZOLE TO FORM A 2-ALKYL-6-AMINO-BENZOXAZOLE IN WHICH THE 2-ALKYL GROUP IS UNBRANCHED AT THE ALPHA CARBON; COUPLERS EASTMAN KODAK COMPANY 2001-03-13 US disclosed
US-T980004-I4 Phenolic dye-forming couplers EASTMAN KODAK COMPANY (US) 1979-03-06 US disclosed
US-4124396-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1978-11-07 US disclosed
US-4124396-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1978-11-07 US disclosed
US-4124396-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1978-11-07 US disclosed