Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457643 | 0.81 | EGFR (0.47) | ALOX15RAB9AKDM4EALDH1A1KDM5A | |
| SCHEMBL28321402 | 0.81 | ALDH1A1 (0.44) | ALOX15CYP3A4GAAMEN1RAB9A | |
| SCHEMBL7745183 | 0.78 | KDM5A (0.59) | GAAMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL565079 | 0.76 | ALOX15 (0.54) | ALOX15CYP3A4HSD17B10GAAMEN1 | |
| SCHEMBL28009999 | 0.76 | ALDH1A1 (0.49) | CYP3A4GAAMEN1RAB9AKMT2A | |
| SCHEMBL11785088 | 0.76 | ALDH1A1 (0.50) | ALOX15CYP3A4MEN1RAB9AKMT2A | |
| SCHEMBL12635347 | 0.76 | ALDH1A1 (0.40) | GAAMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL10579478 | 0.76 | KDM4E (0.53) | ALOX15CYP3A4HSD17B10MEN1RAB9A | |
| SCHEMBL10961434 | 0.74 | CTDSP1 (0.50) | ALOX15CYP3A4HSD17B10GAAMEN1 | |
| SCHEMBL14355319 | 0.74 | ALOX15 (0.59) | ALOX15CYP3A4HSD17B10GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113006-A1 | Process for the synthesis of 2,5-dicarbonamidophenolic couplers and benzoxazole derivatives as intermediates | EASTMAN KODAK COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6201125-B1 | REDUCING A 2-ALKYL-6-NITRO-BENZOXAZOLE TO FORM A 2-ALKYL-6-AMINO-BENZOXAZOLE IN WHICH THE 2-ALKYL GROUP IS UNBRANCHED AT THE ALPHA CARBON; COUPLERS | EASTMAN KODAK COMPANY | 2001-03-13 | — | — | US | disclosed |