Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26630273 | 0.73 | MAPT (0.51) | MAPTRAB9ALMNAACHECNR2 | |
| SCHEMBL7745218 | 0.73 | MAPT (0.52) | MAPTLMNAACHECNR2CNR1 | |
| SCHEMBL28483269 | 0.70 | CNR2 (0.42) | MAPTLMNAACHECNR2CNR1 | |
| SCHEMBL30695536 | 0.70 | CNR2 (0.42) | MAPTLMNAACHECNR2CNR1 | |
| SCHEMBL7745128 | 0.69 | EGLN3 (0.48) | NPC1TDP1RAB9ALMNAMEN1 | |
| SCHEMBL7745534 | 0.69 | EGLN3 (0.48) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL22151023 | 0.69 | CNR2 (0.43) | MAPTLMNAACHECNR2CNR1 | |
| SCHEMBL2537529 | 0.69 | RIPK1 (0.60) | MAPTALDH1A1KDM4ENPC1TDP1 | |
| SCHEMBL28642046 | 0.68 | RIPK1 (0.71) | MAPTALDH1A1KDM4ENPC1TDP1 | |
| SCHEMBL29822933 | 0.68 | RIPK1 (0.71) | MAPTALDH1A1KDM4ENPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |