Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745480 | 0.83 | TOP2A (0.47) | TOP2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7747969 | 0.82 | TOP2A (0.46) | TOP2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7745467 | 0.82 | TOP2A (0.49) | TOP2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7740578 | 0.82 | TOP2A (0.46) | TOP2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7745595 | 0.80 | LMNA (0.65) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7740999 | 0.80 | HTR2A (0.61) | TOP2APOLBKDM4EALDH1A1HPGD | |
| SCHEMBL5858823 | 0.80 | POLB (0.48) | TOP2APOLBALDH1A1HPGDKMT2A | |
| SCHEMBL7744925 | 0.79 | POLB (0.47) | TOP2APOLBKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5859906 | 0.79 | POLB (0.47) | POLBALDH1A1HPGDKMT2ARECQL | |
| SCHEMBL11826363 | 0.78 | CYP2D6 (0.59) | TOP2APOLBKDM4EALDH1A1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |