Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316385 | 0.82 | HTT (0.57) | BCAT2ALDH1A1ERN1PARP1CDC7 | |
| SCHEMBL7762502 | 0.81 | BCAT2 (0.56) | BCAT2SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL5023244 | 0.78 | PARP1 (0.50) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL29456755 | 0.78 | KIT (0.44) | ALDH1A1ADORA2AMEN1POLBMAPT | |
| SCHEMBL8197756 | 0.77 | NQO1 (0.54) | KDM4EALDH1A1ERN1MAPTSMN1; SMN2 | |
| SCHEMBL28187515 | 0.76 | BCAT2 (0.58) | BCAT2SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL31281188 | 0.76 | TSHR (0.49) | KDM4EALDH1A1PARP15PARP10PARP1 | |
| SCHEMBL535683 | 0.76 | TSHR (0.49) | KDM4EALDH1A1PARP15PARP10PARP1 | |
| SCHEMBL21824069 | 0.75 | ENPP2 (0.47) | ALDH1A1ERN1MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL22445134 | 0.75 | TSHR (0.47) | KDM4EALDH1A1PARP15PARP10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129075-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027820-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2000-05-18 | — | — | WO | disclosed |