Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 11/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745356 | 0.82 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL7750310 | 0.82 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8080074 | 0.69 | SHBG (0.57) | AR | |
| SCHEMBL8064054 | 0.68 | SRD5A1 (0.56) | SRD5A1SRD5A2AR | |
| SCHEMBL9113599 | 0.65 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL9113602 | 0.65 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL8725617 | 0.63 | KMT2A (0.37) | SRD5A1SRD5A2AR | |
| SCHEMBL8073932 | 0.63 | SRD5A1 (0.60) | SRD5A1SRD5A2 | |
| SCHEMBL8073934 | 0.63 | SRD5A1 (0.60) | SRD5A1SRD5A2 | |
| SCHEMBL8722257 | 0.63 | SRD5A1 (0.56) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649306-B1 | ESTER DERIVATIVES OF 4-AZA-STEROIDS | MERCK & CO INC (US) | 2001-01-10 | — | — | EP | claimed |