Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6196650 | 0.86 | POLB (0.58) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| Hydrochloric Acid SCHEMBL6199453 | 0.82 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL6491181 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL6491185 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL29897705 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL3030049 | 0.81 | LMNA (0.69) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL3017804 | 0.80 | MEN1 (0.66) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL3029547 | 0.80 | TSHR (0.56) | ALDH1A1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL1546613 | 0.77 | LMNA (0.46) | LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL4551788 | 0.76 | POLB (0.60) | ALDH1A1LMNASMN1; SMN2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400522-B1 | COMPOUNDS FOR TREATING IMPOTENCE | GUANGZHOU YOUCARE BIOPHARMACEATICS CO LTD (CN) | 2014-08-06 | — | — | EP | disclosed |
| WO-2001019827-A1 | A NOVEL PROCESS FOR THE SYNTHESIS OF SILDENAFIL CITRATE | CIPLA LTD. (IN) | 2001-03-22 | — | — | WO | disclosed |