Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491185 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL6491181 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL29897709 | 0.90 | APEX1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL6490243 | 0.90 | APEX1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL6490246 | 0.90 | APEX1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL3029547 | 0.87 | TSHR (0.56) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL25926241 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL25925529 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL7745394 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL6691847 | 0.80 | LMNA (0.44) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113350301-B | New compound traditional Chinese medicine honeyed pill for treating impotence | 刘宝顺 | 2022-10-04 | — | — | CN | claimed |
| CN-116262118-A | Application of alidenafil or salt thereof in preparation of medicines for preventing or treating ischemic brain injury | 真奥金银花药业有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-113350301-B | New compound traditional Chinese medicine honeyed pill for treating impotence | 刘宝顺 | 2022-10-04 | — | — | CN | disclosed |