Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740999 | 0.82 | HTR2A (0.61) | LMNAPKMPOLBHTTSMN1; SMN2 | |
| SCHEMBL23927879 | 0.80 | TDP1 (0.70) | LMNAPKMTDP1CYP11B1CYP11B2 | |
| SCHEMBL7746704 | 0.80 | TOP2A (0.55) | LMNAPKMPOLBHTTMAPK1 | |
| SCHEMBL7747969 | 0.79 | TOP2A (0.46) | LMNAPKMPOLBMEN1KMT2A | |
| SCHEMBL7745134 | 0.79 | HTR2A (0.47) | LMNAPKMPOLBHTTSMN1; SMN2 | |
| SCHEMBL5858823 | 0.77 | POLB (0.48) | LMNATDP1POLBKMT2AALDH1A1 | |
| SCHEMBL7745467 | 0.77 | TOP2A (0.49) | LMNAPOLBMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5859906 | 0.76 | POLB (0.47) | LMNAPKMTDP1POLBKMT2A | |
| SCHEMBL7744925 | 0.76 | POLB (0.47) | LMNAPKMPOLBMAPK1MEN1 | |
| SCHEMBL7745480 | 0.75 | TOP2A (0.47) | LMNAPKMPOLBMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |