Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740999 | 0.86 | HTR2A (0.61) | HTR2AHTR2CPOLBLMNAPKM | |
| SCHEMBL7745595 | 0.79 | LMNA (0.65) | POLBLMNAPKMALDH1A1MEN1 | |
| SCHEMBL3892738 | 0.78 | HTR2A (0.57) | HTR2AHTR2CMTNR1AHTR7DRD3 | |
| SCHEMBL7746704 | 0.74 | TOP2A (0.55) | POLBLMNAPKMTOP2AALDH1A1 | |
| SCHEMBL7745745 | 0.74 | PKM (0.57) | HTR2AHTR2CPOLBLMNAPKM | |
| SCHEMBL7747969 | 0.74 | TOP2A (0.46) | POLBLMNAPKMTOP2AALDH1A1 | |
| SCHEMBL7744925 | 0.73 | POLB (0.47) | POLBLMNAPKMTOP2AALDH1A1 | |
| SCHEMBL5858823 | 0.72 | POLB (0.48) | POLBLMNATOP2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5859906 | 0.71 | POLB (0.47) | POLBLMNAPKMALDH1A1HPGD | |
| SCHEMBL7745480 | 0.70 | TOP2A (0.47) | POLBLMNAPKMTOP2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |