Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775687 | 0.99 | SOAT1 (0.44) | SOAT1MAPK1LMNARAB9ACETP | |
| SCHEMBL774744 | 0.99 | SOAT1 (0.44) | SOAT1MAPK1LMNARAB9ACETP | |
| SCHEMBL775558 | 0.85 | SOAT1 (0.43) | SOAT1MAPK1NPC1LMNACA1 | |
| SCHEMBL776835 | 0.84 | SOAT1 (0.46) | SOAT1LMNACA1CA2RAB9A | |
| SCHEMBL774986 | 0.84 | SOAT1 (0.46) | SOAT1LMNACA1CA2RAB9A | |
| SCHEMBL776246 | 0.76 | PTPN1 (0.42) | MAPK1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL24465104 | 0.72 | NPC1 (0.40) | SOAT1MAPK1NPC1LMNACA1 | |
| SCHEMBL27358463 | 0.72 | CETP (0.43) | SOAT1NPC1LMNACA1CA2 | |
| SCHEMBL14292212 | 0.71 | GAA (0.43) | MAPK1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL12726010 | 0.68 | DEGS1 (0.51) | SOAT1MAPK1NPC1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |