Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745732 | 0.93 | TSHR (0.46) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7740752 | 0.92 | DRD2 (0.44) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7741370 | 0.90 | TSHR (0.43) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7745883 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2PPARGALDH1A1LMNA | |
| SCHEMBL7745254 | 0.88 | TSHR (0.41) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7740725 | 0.87 | TSHR (0.45) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7745243 | 0.85 | TSHR (0.40) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7745239 | 0.85 | TSHR (0.41) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7741297 | 0.83 | TSHR (0.50) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL7745214 | 0.83 | TSHR (0.47) | TSHRMAPK1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |