Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745904 | 0.92 | DRD2 (0.44) | HDAC1HDAC6ALDH1A1POLBHDAC3 | |
| SCHEMBL7745810 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2PPARGALDH1A1POLB | |
| SCHEMBL7745909 | 0.85 | ALDH1A1 (0.35) | HDAC1HDAC6PPARGALDH1A1POLB | |
| SCHEMBL7745471 | 0.85 | ALDH1A1 (0.34) | HDAC1HDAC6ALDH1A1POLBHDAC3 | |
| SCHEMBL7740984 | 0.83 | TBXA2R (0.38) | AGTR1AGTR2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL7741406 | 0.81 | DRD2 (0.44) | ALDH1A1POLBLMNAMAPT | |
| SCHEMBL7740752 | 0.81 | DRD2 (0.44) | ALDH1A1POLBLMNAMAPT | |
| SCHEMBL7745732 | 0.81 | TSHR (0.46) | ALDH1A1POLBLMNAMAPT | |
| SCHEMBL7745974 | 0.80 | DRD2 (0.42) | ALDH1A1POLBLMNAMAPT | |
| SCHEMBL7741370 | 0.78 | TSHR (0.43) | ALDH1A1POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |