Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DTYMK | P23919 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822007 | 0.85 | PAOX (0.34) | MAPK1CYP1A2CYP2C19GAATDP1 | |
| SCHEMBL9116975 | 0.84 | PAOX (0.36) | MAPK1CYP1A2CYP2C19GAATDP1 | |
| SCHEMBL8952508 | 0.82 | KDM4E (0.36) | KDM4EMAPK1ALDH1A1POLBGAA | |
| SCHEMBL8952638 | 0.82 | KDM4E (0.36) | KDM4EMAPK1ALDH1A1POLBGAA | |
| SCHEMBL8002920 | 0.82 | — | — | |
| SCHEMBL9392011 | 0.81 | KMT2A (0.38) | KDM4EHSD17B10MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL8952262 | 0.80 | MAPK1 (0.34) | KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL8952545 | 0.80 | EPHX2 (0.33) | MAPK1ALDH1A1 | |
| SCHEMBL11294427 | 0.79 | EPHX2 (0.38) | MAPK1 | |
| SCHEMBL9419703 | 0.79 | DAO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998014181-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-09 | — | — | WO | claimed |
| WO-2001021166-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-29 | — | — | WO | disclosed |
| US-5922757-A | ADMINISTERING ALPHA-TOCOPHEROL TO PATIENTS WITH HEPATITIS C WHO ARE REFRACTORY TO INTERFERON | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-07-13 | — | — | US | disclosed |
| US-5922757-A | ADMINISTERING ALPHA-TOCOPHEROL TO PATIENTS WITH HEPATITIS C WHO ARE REFRACTORY TO INTERFERON | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-07-13 | — | — | US | disclosed |
| WO-1998014181-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-09 | — | — | WO | disclosed |