Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090211 | 0.90 | MTNR1B (0.62) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| SCHEMBL12520413 | 0.81 | MTNR1B (0.60) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| SCHEMBL6863752 | 0.81 | MGLL (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| Isopropyl Alcohol SCHEMBL28077970 | 0.80 | CNR1 (0.48) | MTNR1BMTNR1ACNR1CYP1A2CYP3A4 | |
| SCHEMBL7505384 | 0.80 | MTNR1B (0.59) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| SCHEMBL11114174 | 0.79 | MTNR1A (0.66) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| SCHEMBL7785497 | 0.79 | MTNR1B (0.51) | MTNR1BMTNR1AMEN1KMT2AMAOB | |
| SCHEMBL11641239 | 0.79 | MTNR1B (0.57) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| SCHEMBL5604615 | 0.79 | MTNR1B (0.57) | MTNR1BMTNR1AMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7505379 | 0.79 | MTNR1B (0.57) | MTNR1BMTNR1AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091736-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-1091736-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001382-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |