Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815618 | 0.92 | CA1 (0.37) | MEN1KMT2ANR1H2NR1H3CA1 | |
| SCHEMBL6811728 | 0.87 | CA1 (0.38) | NR1H2NR1H3CA1CA2CA9 | |
| SCHEMBL6819495 | 0.84 | CA1 (0.45) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL7161462 | 0.81 | KMT2A (0.40) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL6814849 | 0.80 | CYP1A2 (0.43) | MEN1KMT2ATDP1RORCHDAC1 | |
| SCHEMBL7745941 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2ARORCSMN1; SMN2POLB | |
| SCHEMBL6818985 | 0.80 | POLB (0.46) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL6814933 | 0.79 | SMN1; SMN2 (0.53) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL6815906 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2ACA1CA2SMN1; SMN2 | |
| SCHEMBL6819323 | 0.77 | CACNA1B (0.51) | MEN1KMT2AHDAC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |