Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745952 | 0.86 | RAB9A (0.45) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7745960 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7741635 | 0.79 | NPC1 (0.43) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7740722 | 0.74 | MEN1 (0.54) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7740409 | 0.72 | MEN1 (0.42) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7745194 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2APOLBNPC1 | |
| SCHEMBL18543026 | 0.69 | RAB9A (0.52) | SMN1; SMN2MEN1KMT2APOLBNPC1 | |
| SCHEMBL3824637 | 0.67 | TSHR (0.48) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL15416721 | 0.67 | KMT2A (0.56) | SMN1; SMN2USP2MEN1KMT2AL3MBTL1 | |
| SCHEMBL15416463 | 0.67 | MEN1 (0.41) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |