Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745952 | 0.84 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7745960 | 0.81 | SMN1; SMN2 (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7745944 | 0.79 | SMN1; SMN2 (0.36) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7740722 | 0.72 | MEN1 (0.54) | SMN1; SMN2MAPTMEN1USP2KMT2A | |
| SCHEMBL7740409 | 0.70 | MEN1 (0.42) | SMN1; SMN2MEN1USP2KMT2AL3MBTL1 | |
| SCHEMBL7745194 | 0.68 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18543026 | 0.68 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2544715 | 0.66 | NPBWR1 (0.55) | SMN1; SMN2CA1CA2CA12CA9 | |
| SCHEMBL7741640 | 0.66 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL15416721 | 0.66 | KMT2A (0.56) | SMN1; SMN2MAPTMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |