Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172321 | 1.00 | NCF1 (0.44) | NCF1NQO2NQO1HRH3TDO2 | |
| SCHEMBL7746065 | 0.87 | NCF1 (0.44) | NCF1NQO2NQO1HRH3TDO2 | |
| SCHEMBL18861724 | 0.81 | NQO2 (0.44) | NCF1NQO2NQO1TDO2ACKR3 | |
| SCHEMBL3631150 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HDAC1 | |
| SCHEMBL17678182 | 0.80 | NCF1 (0.44) | NCF1NQO2NQO1HRH3ALDH1A1 | |
| SCHEMBL16803415 | 0.80 | NCF1 (0.44) | NCF1NQO2NQO1HRH3ALDH1A1 | |
| SCHEMBL30532037 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HDAC1 | |
| SCHEMBL17845346 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HDAC1 | |
| SCHEMBL7088249 | 0.78 | SMN1; SMN2 (0.44) | HDAC1FLT3 | |
| SCHEMBL24869051 | 0.78 | FLT3 (0.42) | NCF1NQO2NQO1TDO2ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |