Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088249 | 0.90 | SMN1; SMN2 (0.44) | HDAC1HDAC3PRSS1FLT3 | |
| SCHEMBL7746058 | 0.87 | NCF1 (0.44) | NCF1NQO2NQO1HDAC1ALDH1A1 | |
| SCHEMBL31172321 | 0.87 | NCF1 (0.44) | NCF1NQO2NQO1HDAC1ALDH1A1 | |
| SCHEMBL15585982 | 0.83 | NCF1 (0.47) | NCF1ALDH1A1NPSR1HRH3PRSS1 | |
| SCHEMBL11720142 | 0.81 | HDAC6 (0.55) | NCF1ALDH1A1NPSR1HRH3PRSS1 | |
| SCHEMBL17678059 | 0.80 | NCF1 (0.44) | NCF1NQO2NQO1ALDH1A1NPSR1 | |
| SCHEMBL7745728 | 0.80 | ALDH1A1 (0.48) | NCF1ALDH1A1NPSR1HRH3SLC6A2 | |
| SCHEMBL18861724 | 0.78 | NQO2 (0.44) | NCF1NQO2NQO1ALDH1A1NPSR1 | |
| SCHEMBL5017658 | 0.77 | HDAC1 (0.47) | HDAC1HDAC3PRSS1 | |
| SCHEMBL4054487 | 0.77 | HDAC1 (0.44) | HDAC1HDAC3ALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |