Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745730 | 0.91 | DRD2 (0.34) | TP53ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL7745634 | 0.82 | ALDH1A1 (0.37) | ALDH1A1LMNAPOLBTSHRSMN1; SMN2 | |
| SCHEMBL7745443 | 0.77 | CYP3A4 (0.37) | TP53ALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL7745936 | 0.75 | TSHR (0.41) | TP53ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL8366756 | 0.75 | ALDH1A1 (0.38) | TP53ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL8363973 | 0.74 | ALDH1A1 (0.38) | TP53ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL7741233 | 0.72 | TBXA2R (0.34) | TBXA2R | |
| SCHEMBL8363907 | 0.72 | ALDH1A1 (0.43) | TP53ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL8365753 | 0.72 | TP53 (0.42) | TP53ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL7745732 | 0.72 | TSHR (0.46) | TP53ALDH1A1LMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |