SCHEMBL7746205

SCHEMBL7746205

Cc1ccc(C(=CCCl)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
HTT P42858 3/20 0.41
NPSR1 Q6W5P4 3/20 0.41
LMNA P02545 3/20 0.41
HPGD P15428 3/20 0.41
KMT2A Q03164 3/20 0.41
PKM P14618 2/20 0.41
ATM Q13315 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
NLRP1 Q9C000 1/20 0.41
NTSR1 P30989 1/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
BCL2L1 Q07817 1/20 0.40
GSK3B P49841 1/20 0.39
PTGS2 P35354 1/20 0.38
TBXAS1 P24557 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8689509 0.92 NPC1 (0.48) ALDH1A1LMNAHPGDKMT2ASMN1; SMN2
SCHEMBL8689513 0.92 NPC1 (0.48) ALDH1A1LMNAHPGDKMT2ASMN1; SMN2
SCHEMBL6419890 0.79 ALDH1A1 (0.43) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL3005984 0.77 PPARD (0.41) LMNAHPGDSMN1; SMN2TDP1CES2
SCHEMBL8523527 0.77 ALDH1A1 (0.41) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL5673180 0.77 ALDH1A1 (0.41) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL7242171 0.76 MTNR1A (0.47) ALDH1A1NPSR1GSK3BTBXAS1
SCHEMBL8398701 0.74 ALDH1A1 (0.52) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL5146808 0.74 ALDH1A1 (0.39) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL4631622 0.72 NPC1 (0.50) ALDH1A1LMNAHPGDKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0812820-B1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM TAKASAGO PERFUMERY CO LTD (JP) 2001-01-17 EP disclosed
US-6172264-B1 REACTING A TRIPHENYLAMINE WITH A VILSMEIER IN PRESENCE OF ACID CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-09 US disclosed
US-6150065-A 1-(P-AMINOPHENYL)-1,4,4-TRIPHENYLBUTADIENE DERIVATIVE CHARGE TRANSFER COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-11-21 US disclosed
US-5989765-A CHARGE TRANSPORT MATERIAL IS A TRIPHENYLAMINE DERIVATIVE WHERE ONE OF THE PHENYL GROUPS OF THE TRIPHENYL AMINE HAS A DIPHENYLBUTADIENYL-SUBSTITUENT AND THE OTHER TWO PHENYL GROUPS HAVE A DIPHENYLBUTADIENYL- OR DIPHENYLVINYL-FRAMEWORK TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-11-23 US disclosed
US-5910610-A Triphenylamine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-06-08 US disclosed
EP-0650956-B1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives TAKASAGO PERFUMERY CO LTD (JP) 1998-07-15 EP disclosed
US-5736284-A HIGH SOLUBILITY IN POLYMER BINDER TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-04-07 US disclosed
EP-0812820-A1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM Takasago International Corporation (JP) 1997-12-17 EP disclosed
US-5573878-A HIGH CHARGING POTENTIALS, HIGH CARRIER MOBILITY TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-11-12 US disclosed
US-5567560-A Triphenylamine derivative charge-transporting material containing electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-10-22 US disclosed
EP-0650956-A1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives Takasago International Corporation (JP) 1995-05-03 EP disclosed