Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247006 | 0.79 | NISCH (0.45) | ATMNISCHCYP2C9MEN1ALDH1A1 | |
| SCHEMBL30255446 | 0.78 | ALDH1A1 (0.39) | ATMNISCHCYP2C9KDM4EMEN1 | |
| SCHEMBL2406500 | 0.78 | ALDH1A1 (0.39) | ATMNISCHCYP2C9KDM4EMEN1 | |
| SCHEMBL30262472 | 0.74 | LMNA (0.39) | ATMCYP2C9KDM4EMEN1ALDH1A1 | |
| SCHEMBL9816846 | 0.74 | LMNA (0.39) | ATMCYP2C9KDM4EMEN1ALDH1A1 | |
| SCHEMBL5179080 | 0.72 | CYP2C9 (0.34) | ATMNISCHCYP2C9KDM4EMEN1 | |
| SCHEMBL7688752 | 0.72 | CYP2C9 (0.32) | ATMCYP2C9MEN1KMT2A | |
| SCHEMBL1771262 | 0.70 | ANPEP (0.37) | ATMNISCHCYP2C9KDM4EMEN1 | |
| SCHEMBL3397792 | 0.70 | HTR2A (0.38) | KDM4EHSD17B10 | |
| SCHEMBL1871722 | 0.68 | PARP1 (0.35) | ATMCYP2C9KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001019820-A1 | SUBSTITUTED PYRAZOL-3-YLBENZOXAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | claimed |
| WO-2001019820-A1 | SUBSTITUTED PYRAZOL-3-YLBENZOXAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| WO-2001019820-A1 | SUBSTITUTED PYRAZOL-3-YLBENZOXAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |