Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746650 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL1334670 | 0.81 | POLB (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL10941845 | 0.78 | ESR1 (0.49) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6778747 | 0.76 | NPC1 (0.55) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL3043454 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL12368118 | 0.75 | TSHR (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL11472981 | 0.75 | LPAR1 (0.44) | SMN1; SMN2ALDH1A1HTTTRPM8KDM4E | |
| SCHEMBL5656279 | 0.74 | L3MBTL1 (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL5655779 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL11136125 | 0.74 | KDM4E (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010798-A1 | SOLID PHASE SYNTHESIS OF OXA- AND THIAZOLES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-02-15 | — | — | WO | disclosed |