SCHEMBL774670

SCHEMBL774670

CCO[Si](C)(CCCN1CCNCC1)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.42
SIGMAR1 Q99720 2/20 0.37
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GNAI3 P08754 3/20 0.35
GNAO1 P09471 3/20 0.35
GNAI1 P63096 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
SOD3 P08294 2/20 0.34
HRH2 P25021 2/20 0.34
HRH1 P35367 2/20 0.34
HRH3 Q9Y5N1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063237 0.95 CXCR4 (0.43) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL31687741 0.92 CXCR4 (0.39) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL4063799 0.89 SIGMAR1 (0.37) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL28769738 0.89 CXCR4 (0.37) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL11655734 0.87 CXCR4 (0.40) CXCR4SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL4063049 0.86 CXCR4 (0.42) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL31265242 0.85 CYP3A4 (0.40) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL2401145 0.84 CXCR4 (0.43) CXCR4SIGMAR1POLBSMN1; SMN2HSD17B10
SCHEMBL12002829 0.84 PAOX (0.38) SIGMAR1GNAI3GNAO1GNAI1DRD3
SCHEMBL1991943 0.84 HRH3 (0.41) SMN1; SMN2HRH3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112280041-B Preparation method of amino silicone oil with low organosilicon ring body content 江西蓝星星火有机硅有限公司 2022-05-27 CN claimed
CN-112280041-A Preparation method of amino silicone oil with low organosilicon ring body content 江西蓝星星火有机硅有限公司 2021-01-29 CN claimed
CN-108624105-B Preparation method of water-soluble antifouling anti-doodling auxiliary agent 太仓中化环保化工有限公司 2020-10-20 CN claimed
CN-105601934-B Modified double-end amino dimethyl silicone polymer of ammonia hydrocarbyl side chain and preparation method thereof 广州市东雄化工有限公司 2019-04-09 CN claimed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
CN-119708547-A Metal-coated organic silicon resin microsphere and preparation method and application thereof 江苏涌新材料科技有限公司 2025-03-28 CN disclosed
CN-116042091-B Preparation method of amino/phenyl fluorosilicone resin composite epoxy styrene-acrylic paint and coating 陕西科技大学 2024-04-26 CN disclosed
CN-117903696-A Water-based modified fluorosilicone resin coating composition, coating and preparation method thereof 东莞市雄驰电子有限公司 2024-04-19 CN disclosed
CN-117820646-A Amino silane ring-opened epoxy resin modified fluorosilicone resin aqueous emulsion, preparation method and application 东莞市雄驰电子有限公司 2024-04-05 CN disclosed
CN-116042091-A Preparation method of amino/phenyl fluorosilicone resin composite epoxy styrene-acrylic paint and coating 陕西科技大学 2023-05-02 CN disclosed
CN-112280041-B Preparation method of amino silicone oil with low organosilicon ring body content 江西蓝星星火有机硅有限公司 2022-05-27 CN disclosed
CN-112280041-A Preparation method of amino silicone oil with low organosilicon ring body content 江西蓝星星火有机硅有限公司 2021-01-29 CN disclosed
US-20080194440-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS RAVICHANDRAN RAMANATHAN 2008-08-14 US disclosed
EP-1714968-B1 Protected piperazino group-bearing organoxysilane compound and making method SHINETSU CHEMICAL CO (JP) 2008-07-16 EP disclosed
EP-1907517-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS King Industries, Inc. (US) 2008-04-09 EP disclosed
US-20070042917-A1 Amine Tungstates and Lubricant Compositions KING INDUSTRIES, INC. 2007-02-22 US disclosed
WO-2007009022-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. (US) 2007-01-18 WO disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed
US-4098840-A THERMOSETTING RESIN COMPOSITION JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM CXCR4 3143/4885SIGMAR1 1050/4885POLB 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.