Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741461 | 0.83 | TSHR (0.48) | TSHRGFERALDH1A1HSD17B10CHRM1 | |
| SCHEMBL7740571 | 0.83 | TSHR (0.56) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7741428 | 0.80 | TSHR (0.52) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL21169559 | 0.79 | TSHR (0.53) | TSHRGFERALDH1A1CHRM1LMNA | |
| SCHEMBL7745697 | 0.78 | TSHR (0.64) | TSHRMAPK1ALDH1A1TP53POLB | |
| SCHEMBL7740562 | 0.78 | TSHR (0.57) | TSHRMAPK1ALDH1A1CHRM1TP53 | |
| SCHEMBL3727049 | 0.77 | TSHR (0.54) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL16163238 | 0.76 | TSHR (0.53) | TSHRMAPK1 | |
| SCHEMBL3738360 | 0.76 | TSHR (0.53) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7741104 | 0.76 | TSHR (0.55) | TSHRMAPK1ALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |