Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7746018 | 0.95 | ACHE (0.38) | ACHETDP1MAOACA7MAOB | |
| Iodide SCHEMBL7192916 | 0.80 | ACHE (0.42) | ACHETDP1MAOACA7MAOB | |
| Iodide SCHEMBL5029340 | 0.78 | HIF1A (0.52) | MAOASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7196441 | 0.75 | ACHE (0.42) | ACHETDP1MAOACA7MAOB | |
| Bromide SCHEMBL5074601 | 0.75 | ACHE (0.42) | ACHETDP1MAOACA7MAOB | |
| Hydrochloric Acid SCHEMBL8086728 | 0.73 | HIF1A (0.52) | MAOASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| Bromide SCHEMBL161462 | 0.73 | HIF1A (0.52) | MAOASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| Iodide SCHEMBL7197935 | 0.71 | SNCA (0.44) | ACHETDP1HPGDIDO1ALDH1A1 | |
| Iodide SCHEMBL9067569 | 0.71 | ACHE (0.50) | ACHETDP1MAOACA7MAOB | |
| SCHEMBL8376846 | 0.68 | HIF1A (0.46) | MAOASLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001016204-A1 | PROCESS FOR UPSTAGING EPOXY RESINS | RESOLUTION RESEARCH NEDERLAND B.V. (NL) | 2001-03-08 | — | — | WO | disclosed |